PROPIOLACTONE BETA

Part No: RXSOL-19-1427-210

PROPIOLACTONE BETA

Category
Solvent Chemicals

Beta-Propiolactone (β-Propiolactone)  - Not for SALE

Beta-Propiolactone (BPL) is a highly reactive, four-membered cyclic ester (lactone) used primarily as a specialty chemical intermediate and in certain controlled laboratory and industrial applications.

Application

Applications

  • Specialty chemical synthesis

  • Pharmaceutical and biochemical research

  • Polymer and materials research

  • Chemical intermediate

  • Controlled laboratory applications

Dose

Technical specifications
PRODUCT NAME     : PROPIOLACTONE (BETA-)        
CAS number       : 57-57-8
UN number       :  
Formula        : OCH2CH2CO
Odour         : PUNGENT
Solubility in water        : SOLUBLE
Density    : 1.146   at 20    oC
Boiling point          :  155 oC
Melting point            :  -33 oC
Viscosity        :  
Flashpoint            : 75 oC
Explosive limits       : 2.9 - ? Vol%
Vapour pressure     : 3 mbar at 20    oC
Skin absorption/irritation       : YES
TLV       Country  NL              Year  1995     : 0.5 ppm                1.5       mg/m3
Pollution category    1994            : D
Supply location

PROPIOLACTONE BETA manufacturer supplier distributor in Mumbai, Kandla, Kolkata, Vizag, Chennai, India, Fujairah, Dubai UAE, Muscat Oman, Kenya Africa. Get the best quality of PROPIOLACTONE BETA at a competitive price from us. We have ready stock of PROPIOLACTONE BETA in India, UAE Gulf, Oman, Kenya Africa. Contact us for bulk as well as small orders.

Note

Important: Beta-propiolactone is a highly hazardous, reactive chemical and a recognized carcinogenic substance. It requires strictly controlled industrial/laboratory handling, appropriate engineering controls, PPE, storage, transportation, and regulatory compliance. It should not be handled or used outside a properly equipped professional facility.

Safety Data (MSDS)

Product Name               PROPIOLACTONE BETA
Part Number   RXSOL-19-1427-210

Company Details:

RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA

Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA  

Phone +91 22 20871200 - 1400
Fax +91 22 27612100 :::AOH :0091 9821214367
Email mail@rxmarine.com
Website www.rxmraine.comA

Chemical  Name                             CAS                         EC number                      Weight                             
Beta-Propiolactone 57-57-8 --       = 100 %       

Signal Word  Danger
Hazard Statements Combustible liquid Causes skin irritation Causes serious eye irritation Fatal if inhaled May cause cancer
Precautionary statements   Obtain special instructions before use Do not handle until all safety precautions have been read and understood Use personal protective equipment as required Do not breathe dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area Wear respiratory protection Wash face, hands and any exposed skin thoroughly after handling Wear eye/face protection Keep away from heat/sparks/open flames/hot surfaces. - No smoking Keep cool Response IF exposed or concerned: Get medical attention/advice Inhalation IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Immediately call a POISON CENTER or doctor/physician Skin IF ON SKIN: Wash with plenty of soap and water If skin irritation occurs: Get medical advice/attention Take off contaminated clothing and wash before reuse Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing If eye irritation persists: Get medical advice/attention Fire In case of fire: Use CO2, dry chemical, or foam for extinction Storage Store locked up Store in a well-ventilated place. Keep container tightly closed Disposal Dispose of contents/container to an approved
Classification of the substance or mixture Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.
Supplemental Hazard      Statements EUH032 Contact with acids liberates very toxic gas.
Other hazards  This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

General advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required.
If inhaled  After inhalation: fresh air.
Eye Contact In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Swallowed After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.
Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.
Inhalation Remove to fresh air. If not breathing, give artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required.
Ingestion Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delaye Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomitin
Indication of any immediate medical attention and special treatment needed  No data available

Flammability                                                  Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Suitable extinguishing media Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam. Water mist may be used to cool closed containe
Unsuitable extinguishing media No information available
Special hazards arising from the substance or mixture  Carbon oxides Sulfur oxides Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.
Further information Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Hazardous combustion
products		 Carbon monoxide (CO). Carbon dioxide
Advice for firefighters In the event of fire, wear self-contained breathing apparatus.
Protective Equipment As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and va
Specific Hazards Arising from the Chemical Oxides of phosphorus Sodium oxides Not combustible. Fire may cause evolution of: Oxides of phosphorus Ambient fire may liberate hazardous vapours.

Personal precautions, protective equipment and emergency procedures Use personal protective equipment as required. Ensure adequate ventilation. Keep people away from and upwind of spill/leak. Evacuate personnel to safe areas.
Spillage Oxidizing material. Stop leak if without risk. Avoid contact with a combustible material (wood, paper, oil, clothing...). Keep substance damp using water spray. Do not touch spilled material. Prevent entry into sewers, basements or confined areas dike if needed. Eliminate all ignition sources. Call for assistance on disposal.
Enviromental Precaution Should not be released into the environme
Methods and materials for
containment and cleaning		 Keep in suitable, closed containers for disposal. Soak up with inert absorbent material .

Handling Do not get in eyes, on skin, or on clothing. Wear personal protective equipment/face protection. Use only under a chemical fume hood. Do not breathe mist/vapors/spray. Do not ingest. If swallowed then seek immediate
Storage Keep away from heat, sparks and flame. Protect from light. Store in freezer. Store contents under argon. Keep containers tightly closed in a dry, cool and well-ventilated place. Incompatible Materials. Acids. Bases. Strong oxidizing agents. Strong acids. Strong bases. Halogens.

Exposure controls  Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. 
Control parameters Ingredients with workplace control parameters Contains no substances with occupational exposure limit values.
Engineering Control Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Eye/face protection Tight sealing safety goggles. Face protection
Skin / Body        protection Wear appropriate protective gloves and clothing to prevent skin exosure.
Respiratory protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Other Protection      Measure Handle in accordance with good industrial hygiene and safety practice.
Control of    environmental exposure Do not let product enter drains.

Physical state Liquid
Colour Colorless
Odour pungent
Odor Threshold No data available
pH No data available
Melting Point 33 °C / -27.4 °F
Boiling Point 162 °C / 323.6 °F
Flash Point No data available
Evaporation Rate 70 °C / 158 °F
Flammability (solid, gas) No data available
Explosive limits No Data Available
Upper/lower flammability or explosive limits No data available
Autoignition temperature No data available
Decomposition temperature  155 °C
Vapour pressure 2.90%  
Density No data available                                                            
Relative  Density                                                     2.5 (Air = 1.0)
Relative vapor density No data available
Freezing point  No data available 
Viscosity No data available
Partition coefficient No data available
Explosive properties No data available 
Solubility Miscible with wate
Ignition temperature No information available.
Particle characteristics No data available 

Reactivity                        None known, based on information available
Stability Moisture sensitive.    
Possibility of hazardous reactions No data available
Conditions to avoid Incompatible products. Excess heat. Keep away from open flames, hot surfaces and sources of ignition. Exposure to moist air or water. Exposure to light.
Incompatible materials Acids, Bases, Strong oxidizing agents, Strong acids, Strong bases, Halogen
Hazardous decomposition products Carbon monoxide (CO), Carbon dioxide (CO2)

Acute toxicity  Oral: No data available Inhalation: No data available Dermal: No data available
Skin corrosion/irritation Remarks: No data available
Serious eye      damage/eye       irritation  Remarks: No data available
Respiratory or skin    sensitization  No data available
Toxic Effects on         Human May cause damage to the following organs: upper respiratory tract. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, sensitizer), of ingestion, of inhalation (lung irritant, lung sensitizer).
Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen. May cause cancer.
Germ cell        mutagenicity  No data available
Reproductive toxicity  No data available
Specific target organ toxicity - single      exposure No data available
Special Remarks on other Toxi  Effects on Humans Acute Potential Health Effects: Skin: Causes skin irritation. May cause skin sensitization, an allergic reation, which becomes evident upon re-exposure to this material. Eyes: Causes eye irritation. Ingestion: Causes gastrointestinal (digestive) tract irritation with nausea, vomiting, and diarrhea. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May cause chemical pneumonitis and pulmonary edema, inflammation, edema of bronchi and larynx. Chronic Potential Health Effects: Repeated or prolonged skin exposure may cause allergic reactions in sensitive individuals. Repeated or prolonged exposure by inhalation may affect respiration and metabolism.
Endocrine disrupting properties The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

Bioaccumulative potential No data available
Persistence and            degradability Soluble in water Persistence is unlikely based on information available.
Toxicity to fish  LC50 - Lepomis macrochirus (Bluegill) - 0,24 mg/l - 96 h
Toxicity to daphnia and other aquatic invertebrates Flow-through test EC50 - Ceriodaphnia dubia (water flea) - 0,035 mg/l - 48 h (OECD Test Guideline 202)
Toxicity to algae Flow-through test NOEC - algae - 0,002 mg/l - 7 Days Remarks: (in analogy to similar products) (ECHA) The value is given in analogy to the following substances: sodium hypochlorite solution
Toxicity to bacteria  Static test EC50 - activated sludge - 563 mg/l - 3 h (OECD Test Guideline 209) Remarks: (in analogy to similar products) The value is given in analogy to the following substances: sodium hypochlorite solution
Mobility in soil Will likely be mobile in the environment due to its water  solubility.
Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Endocrine disrupting       properties The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Other adverse effects No data available

Disposal methods The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging Dispose of as unused product.
Waste treatment      Method Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification.

UN number ADR/RID:3382           IMDG:3382                   IATA:3382 
UN proper shipping name ADR/RID:beta.-Propiolactone        IMDG: beta.-Propiolactone           IATA:beta.-Propiolactone
Transport hazard class(es) ADR/RID:6.1              IMDG:6.1                     IATA:6.1 
Packaging group ADR/RID:     I             IMDG:   I                      IATA:  I
Environmental hazards ADR/RID:  NO           IMDG: NO                     IATA: NO
Further information No data available                                                                                                                                  

Inventory status Components are on the following inventories: Polymaleic acid: - US TSCA, Canadian DSL, EU EINECS, Australian AICS, Korean, Philippine PICCS and Chinese Xi irritant R 36/38 Irritant to eyes & skin R 41 Risk of serious damage to eyes S24/25 Avoid contact with skin and eyes S26/28 In case of contact eyes & skin, rinse with plenty water and seek medical advice Section 312/313: Not listed. Not listed under California proposition 65. 
Safety, health and environmental regulations/legislation specific for the substance or mixture This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.
Other regulations Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable. Take note of Dir 94/33/EC on the protection of young people at work.  
Chemical Safety Assessment For this product a chemical safety assessment was not carried out

Other Information

The information above is believed to be accurate and represents the  best information   currently    available  to us.  However,   we   make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and  weassume  no liability resulting from its use. Users should make  their  own  investigations  to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International  has been advised of the possibility of such damages.

DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.